Ameloblastoma pathophysiology
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Pathophysiology
Gross
Shown below is the gross specimen of resected left half of mandible initiated at third molar.
Microscopic Pathology
Histopathology will show cells that have the tendency to move the nucleus away from the basement membrane. This process is referred to as "Reverse Polarization". The follicular type will have outer arrangement of columnar or palisaded ameloblast like cells and inner zone of triangular shaped cells resembling stellate reticulum in bell stage. The central cells sometimes degenerate to form central microcysts. The plexiform type has epithelium that proliferates in a "Fish Net Pattern".
The six different histopathological variants of ameloblastoma are desmoplastic, granular cell, basal cell, plexiform, follicular, and acanthomatous.[1]
Video
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References
- ↑ Gruica B, Stauffer E, Buser D, Bornstein M. (2003). "Ameloblastoma of the follicular, plexiform, and acanthomatous type in the maxillary sinus: a case report". Quintessence International. 34 (4): 311–4. PMID 12731620. Unknown parameter
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