Appendicitis causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Appendicitis is mainly caused by the retention and obstruction of fecal matter, parasitic or bacterial infections of the appendix, and by physical damage to the appendix.

Causes

Common Causes

Common causes of appendicitis include:

  • Foreign bodies
  • Trauma
  • Intestinal worms
  • Lymphadenitis
  • The occurrence of an obstructing fecalith
    • The occurrence of a fecalith in the appendix seems to be attributed to a right sided fecal retention reservoir in the colon and a prolonged fecal transit time[1].
  • Low dietary fiber intake
    • Several studies offer evidence that a low fiber intake is involved in the pathogenesis of appendicitis[2][3][4].
    • This link between low fiber intake and appendicitis is in accordance with the occurrence of a right sided fecal reservoir and that dietary fiber reduces fecal transit time[5].
  • Appendicolith
  • Ascariasis
  • Bacteroides
  • Taenia infection

Causes in Alphabetical Order

References

  1. Raahave D, Christensen E, Moeller H. Origin of acute appendicitis: Fecal retention in colonic reservoirs: A case control study. Surg Infect 2007;8:55-61
  2. Burkitt DP, Walker ARP, Painter NS. Effect of dietary fibre on stools and transit-times, and its role in the causation of disease. Lancet 1972;300:1408-12
  3. Adamis D, Roma-Giannikou E, Karamolegou K. Fiber intake and childhood appendicitis. Int J Food Sci Nutr 2000;51:153-7
  4. Hugh TB, Hugh TJ, "Appendicectomy — becoming a rare event?" MJA 2001; 175: 7-8
  5. Gear JSS, Brodribb AJM, Ware A. Fibre and bowel transit times. Br J Nutr 1981;45:77-82

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