Pseudoxanthoma elasticum epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ayokunle Olubaniyi, M.B,B.S [2]
Overview
Epidemiology and Demographics
PXE is a rare disease but the exact prevalence is unknown. The prevalence has been suggested to be approximately 1:50,000,[1] with an estimate of 150,000 affected in the world assuming the same global prevalence.[1] Females are twice as likely to be affected as males, and the average age of onset is 13 years. The disease occurs in all ethnicities, but South Africans are more likely to have PXE as a result of a founder effect (i.e. it was relatively prevalent in the small group of people from whom most South Africans descend).[2]
References
- ↑ 1.0 1.1 Uitto, J. (2012). "Rare heritable skin diseases: targets for regenerative medicine". J Invest Dermatol. 132 (11): 2485–8. doi:10.1038/jid.2012.334. PMID 23069901. Unknown parameter
|month=ignored (help) - ↑ Allen, P.; Wightman, F. (1992). "Spectral pattern discrimination by children". J Speech Hear Res. 35 (1): 222–33. PMID 1735972. Unknown parameter
|month=ignored (help)