Noonan syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Serge Korjian, Yazan Daaboul

Epidemiology and Demographics

Noonan syndrome is inherited in an autosomal dominant pattern, and despite the disease being congenital, it can manifest at different ages due to its variable expression. In general, males and females have the same incidence of the disease which can be explained by the inheritance pattern. The estimated prevalence in the general population is 1 in 1000 to 2500 individuals.

References

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