Acute pancreatitis resident survival guide
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vidit Bhargava, M.B.B.S [2]
Definition
It is an acute inflammation of the pancreas characterized by elevated pancreatic enzymes and severe abdominal pain.
Causes
Life Threatening Causes
Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. Acute pancreatitis from any cause may be life-threatening especially if it progresses to necrotizing pancreatitis. However, in last several years it has come down due to advances in diagnosis and treatment strategies.
Common Causes
- Trauma[3]
- Medication such as 5-Mercapto-purine, azathioprine, 5-DDI24010098
- Hypertriglyceridemia
- Post - ERCP
- Metabolic - Hypercalcemia and hyperphosphatemia.
- Infections
- Toxins such as venom of brown recluse spider, certain arachnids etc.
- Pregnancy
- Idiopathic
- Ischaemic necrosis of pancreas from vascular sources such as vasculitis and atherosclerosis.
Management
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References
- ↑ Rebours, V.; Vullierme, MP.; Hentic, O.; Maire, F.; Hammel, P.; Ruszniewski, P.; Lévy, P. (2012). "Smoking and the course of recurrent acute and chronic alcoholic pancreatitis: a dose-dependent relationship". Pancreas. 41 (8): 1219–24. doi:10.1097/MPA.0b013e31825de97d. PMID 23086245. Unknown parameter
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ignored (help) - ↑ Köhler, H.; Lankisch, PG. (1987). "Acute pancreatitis and hyperamylasaemia in pancreatic carcinoma". Pancreas. 2 (1): 117–9. PMID 2437571.
- ↑ Bleichner, JP.; Guillou, YM.; Martin, L.; Seguin, P.; Mallédant, Y. (1998). "-Pancreatitis after blunt injuries to the abdomen-". Ann Fr Anesth Reanim. 17 (3): 250–3. PMID 9750738.