Dehydroemetine

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{{Dehydroemetine}} Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Dehydroemetine is a synthetically produced antiprotozoal agent similar to emetine in its anti-amoebic properties and structure (they differ only in a double bond next to the ethyl substituent), but it produces fewer side effects. In the United States, it is manufactured by Roche.

Category

Amebicide

US Brand Names

Mebadin®

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings | Precautions | Adverse Reactions | Overdosage | Clinical Studies | Dosage and Administration | Compatibility, Reconstitution, and Stability | How Supplied | Labels and Packages

Mechanism of action

Its exact mechanism is not known, but in vitro it inhibits translocation.[1]

References

  1. Abdi, Y. A. (1995). Handbook of drugs for tropical parasitic infections. Washington, DC: Taylor & Francis. p. 47. ISBN 0-7484-0168-7.