Polymyxin B sulfate
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
The original ointment contains three different antibiotics: bacitracin, neomycin, and polymyxin B, in a relatively low molecular weight patented base of cocoa butter, cottonseed oil, sodium pyruvate, tocopheryl acetate, and petroleum jelly.
The generic name for these products, regardless of the base, is "Triple Antibiotic Ointment". In China, this product is called "Complex Polymyxin B Ointment," which is manufactured by Zhejiang Reachall Pharmaceutical. The product was also marketed by The Upjohn Company under the name "Mycitracin", until 1997 when that name was acquired by Johnson & Johnson.[1]
Category
US Brand Names
NEOSPORIN®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Dosage and Administration | How Supplied
Mechanism of Action
Polymyxin antibiotic is a surface active agent which penetrates into and disrupts the bacterial cell membrane. It has been shown to have bactericidal activity against most strains of the microorganisms.[2]
References
- ↑ "McNeil Consumer Products Co. strengthens worldwide lead in OTC pain reliever market" (Press Release). Business Wire. Fort Washington, PA: Business Wire. 1997 June 5. Retrieved June 28, 2011 Check date values in:
|publication-date=(help) - ↑ "NEOSPORIN (NEOMYCIN AND POLYMYXIN B SULFATES AND GRAMICIDIN) SOLUTION [MONARCH PHARMACEUTICALS, INC.]". Text " accessdate" ignored (help)