Penicillin G potassium
| Penicillin G potassium |
|---|
| PENICILLIN G POTASSIUM® FDA Package Insert |
| Description |
| Clinical Pharmacology |
| Microbiology |
| Indications and Usage |
| Contraindications |
| Warnings and Precautions |
| Adverse Reactions |
| Overdosage |
| Dosage and Administration |
| How Supplied |
| Labels and Packages |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Buffered Penicillin G Potassium for Injection, USP is sterile penicillin G potassium powder for reconstitution. It is an antibacterial agent intended for intravenous or intramuscularly use. Buffered Penicillin G Potassium for Injection, USP is indicated in the treatment of serious infections caused by susceptible strains of the designated microorganisms in several conditions. Appropriate culture and susceptibility tests should be done before treatment in order to isolate and identify organisms causing infection and to determine their susceptibility to penicillin G.[1]
Category
US Brand Names
PENICILLIN G POTASSIUM®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Overdosage | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
Penicillin G is bactericidal against penicillin-susceptible microorganisms during the stage of active multiplication. It acts by inhibiting biosynthesis of cell-wall mucopeptide. It is not active against the penicillinase-producing bacteria, which include many strains of staphylococci. Penicillin G is highly active in vitro against staphylococci (except penicillinase-producing strains), streptococci (groups A, B, C, G, H, L and M), pneumococci and Nelsseriameningitidis. Other organisms susceptible in vitro to penicillin G are Nelsseriagonorrhoeae, Corynebacteriumdiphtheriae, Bacillus anthracis, clostridia, Actinomycesspecies, Spirillum minus, Streptobacillusmonillformis, Listeria monocytogenes, and leptospira; Treponemapallidumis extremely susceptible.[1]
References
- ↑ 1.0 1.1 "PENICILLIN G POTASSIUM INJECTION, POWDER, FOR SOLUTION [SANDOZ INC]". Text " accessdate" ignored (help)
Adapted from the FDA Package Insert.