Almotriptan contraindications
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Pratik Bahekar, MBBS [2]
Contraindications
- Ischemic heart disease, coronary artery vasospasm, or other significant underlying cardiovascular disease
- Cerebrovascular syndromes (e.g., history of stroke or TIA)
- Peripheral vascular disease (including ischemic bowel disease)
- Uncontrolled hypertension
- Do not use Almotriptan within 24 hours of an ergotamine-containing, or ergot-type medication, or of another 5-HT1 agonist, e.g., another triptan
- Hemiplegic or basilar migraine
- Known hypersensitivity to Almotriptan
Ischemic or Vasospastic Coronary Artery Disease, or Other Significant Underlying Cardiovascular Disease
Do not use Almotriptan (almotriptan malate) in patients with ischemic heart disease (angina pectoris, history of myocardial infarction, or documented silent ischemia), or in patients who have symptoms or findings consistent with ischemic heart disease, coronary artery vasospasm, including Prinzmetal's variant angina, or other significant underlying cardiovascular disease [see Warnings and Precautions
Cerebrovascular Syndromes
Do not use Almotriptan in patients with cerebrovascular syndromes including (but not limited to) stroke of any type as well as transient ischemic attacks [see Warnings and Precautions (5.3)].
Peripheral Vascular Disease
Do not use Almotriptan in patients with peripheral vascular disease including (but not limited to) ischemic bowel disease [see Warnings and Precautions].
Uncontrolled Hypertension
Because Almotriptan may increase blood pressure, do not use Almotriptan in patients with uncontrolled hypertension [see Warnings and Precautions ].
Ergotamine-Containing and Ergot-Type Medications
Do not use Almotriptan and ergotamine-containing or ergot-derived medications like dihydroergotamine, ergotamine tartrate, or methysergide within 24 hours of each other [seeDrug Interactions .
Concomitant Use With 5-HT1 Agonists (e.g., Triptans)
Almotriptan and other 5-HT1 agonists (e.g., triptans) should not be administered within 24 hours of each other [see Warnings and Precautions (5.1) and (5.2)].
Hemiplegic or Basilar Migraine
Do not use Almotriptan in patients with hemiplegic or basilar migraine.
Hypersensitivity
Almotriptan is contraindicated in patients with known hypersensitivity to almotriptan or any of its inactive ingredients.