Sandbox/Alejandro

Therapy based on Anatomical LocationAdapted from

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Location   ▸  Buccal   ▸  Periorbital   ▸  Orbital   ▸  Perianal   ▸  '   ▸  '   ▸  '

Buccal Cellulitis Preferred Regimen ▸ [[ OR ▸ [[ Alternative Regimen ▸ [[ OR ▸ [[ Periorbital Cellulitis Preferred Regimen ▸ [[ OR ▸ [[ Alternative Regimen ▸ [[ OR ▸ [[ Orbital Cellulitis Preferred Regimen ▸ [[ OR ▸ [[ Alternative Regimen ▸ [[ OR ▸ [[ Perianal Cellulitis Preferred Regimen ▸ [[ OR ▸ [[ Alternative Regimen ▸ [[ OR ▸ [[ ## Cellulitis Preferred Regimen ▸ [[ OR ▸ [[ Alternative Regimen ▸ [[ OR ▸ [[

Special ConsiderationsAdapted from

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Special Considerations   ▸  Diabetic Foot Ulcer   ▸  Neutropenic Patients   ▸  Sal Water Wound Exposure   ▸  Fresh Water Wound Exposure   ▸  Butcher, Fisherman, Veterinarian

Diabetic Foot Ulcer Preferred Regimen ▸ Ampicillin–sulbactam 3g IV q6h Alternative Regimen ▸ Meropenem OR ▸ Imipenem-cilastatin OR ▸ Clindamycin PLUS ▸ Ciprofloxacin OR ▸ Levofloxacin OR ▸ Metronizadole PLUS ▸ Ciprofloxacin OR ▸ Levofloxacin OR ▸ Ceftriaxone Neutropenic Patients Preferred Regimen ▸ [[ OR ▸ [[ Alternative Regimen ▸ [[ OR ▸ [[ Salt Water Wound Exposure (Vibrio vulnificus) Preferred Regimen ▸ Doxycycline 200 mg IV initial dose, then 50-100 mg IV q12h PLUS ▸ Regular therapy for cellulitis Alternative Regimen ▸ Cefotaxime OR ▸ Ciprofloxacin Fresh Water Wound Exposure (Aeromonas spp) Preferred Regimen ▸ Ciprofloxacin 400mg IV q12h OR ▸ Ceftazidime PLUS ▸ Gentamicin PLUS ▸ Regular therapy for cellulitis Alternative Regimen ▸ Meropenem OR ▸ Imipenem-cilastatin Butcher, Fisherman, Veterinarian Preferred Regimen ▸ [[ OR ▸ [[ Alternative Regimen ▸ [[ OR ▸ [[

Skin and Soft-Tissue Infections (SSTI)

	Layer	Condition	Definition
File	Epidermis	Impetigo	High contagious superficial skin infection that affects the epidermis. It is classified as bullous and non-bullous, being the latter the most common presentation of impetigo. Bullous impetigo: small vesicles that enlarge to a bullae, commonly associated with S. aureus infection Non-bullous impetigo: characteristic "honey-crust" lesions, can be caused by S. aureus or Streptococi.
		Ecthyma	Severe form of impetigo with ulceration of the epidermis and formation of crust. The legs, thighs and buttocks are the most common affected areas.
	Dermis	Folliculitis	Inflammation of a hair follicle
		Furuncle	Infection of a hair follicle, also known as boil.
		Carbuncle	Collection of furuncles with a larger area of involvement and may extend to the subcutaneous tissue.
		Erysipelas	Superficial skin infection with a clear line of demarcation between involved and uninvolved tissue and raised lesions above the level of the surrounding skin; affects the epidermis and upper dermis.
		Cellulitis	Diffuse skin infection that involves the deeper dermis and the subcutaneous fat tissue. It is classified as non-purulent and purulent cellulitis. Non-purulent cellulitis: with no purulent drainage or exudate and no associated abscess. Purulent cellulitis: associated with purulent drainage or exudate in the absence of a drainable abscess.
	Subcutaneous tissue
		Necrotizing fasciitis
	Muscle	Myonecrosis