Sandbox/table
< Sandbox
The following table contains the main risk factors for CDI:[1][2][3][2][2]
| Alterations in the coagulation system |
|---|
| Consumption of clotting factors |
| Increased concentrations of fibrin degradation products |
| Disseminated intravascular coagulation |
| Organ/Tissue | Effect |
|---|---|
| Endothelial cells | There is no clear evidence of endovascular damage |
| Liver | Causes hepatocellular necrosis which could impair the synthesis of proteins of the coagulation system |
| Adrenal cortex | Affects the synthesis of enzymes responsible for the synthesis of steroids, leading to hypotension, and fluid and electrolytes disturbances. |
| Lymphatic system | [[Necrosis of the spleen, lymph nodes and thymus; Apoptosis of lymphocytes leading to lymphopenia. |
table
| Diagnostic test | North America | South America | Middle East | Far East |
|---|---|---|---|---|
ELISA (serology) detects:
|
† There is a reported prevalence of 15% in the Northeast of the US.
- ↑ Hensgens MP, Goorhuis A, Dekkers OM, Kuijper EJ (2012). "Time interval of increased risk for Clostridium difficile infection after exposure to antibiotics". J Antimicrob Chemother. 67 (3): 742–8. doi:10.1093/jac/dkr508. PMID 22146873.
- ↑ 2.0 2.1 2.2 Knight, Christopher L.; Surawicz, Christina M. (2013). "Clostridium difficile Infection". Medical Clinics of North America. 97 (4): 523–536. doi:10.1016/j.mcna.2013.02.003. ISSN 0025-7125.
- ↑ Planche, Tim (2013). "Clostridium difficile". Medicine. 41 (11): 654–657. doi:10.1016/j.mpmed.2013.08.003. ISSN 1357-3039.