Alprazolam

Synonyms / Brand Names: Aloram, Alprax, Alplax, Alpronax, Alprox, Alzam, Anxirid, Apo-Alpraz, Azor, Calmax, Frontal, Frontin, Gerax, Helex, Kalma, Kinax, Neurol, Novo-Alprazol, Nu-Alpraz, Restyl, Trankimazin, Xanax, Xanor, Zopax, Trika, Bestrol, Cassadan, Constan, D 65MT, Esparon, Intensol, Niravam, Solanax, Tafil, Tranax, Tranquinal, Xanax XR. It is also commonly known as "Totem Poles" or "Ladders" or "Bars" or "Yellow Buses" or "French Fries" when laced, when sold or used illegally.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Dosing and Administration

Treatment for patients with anxiety should be initiated with a dose of 0.25 to 0.5 mg given three times daily.

In elderly patients, in patients with advanced liver disease or in patients with debilitating disease, the usual starting dose is 0.25 mg, given two or three times daily.

In controlled trials conducted to establish the efficacy of Alprazolam in panic disorder, doses in the range of 1 to 10 mg daily were used. The mean dosage employed was approximately 5 to 6 mg daily.

Dosage should be individualized for maximum beneficial effect. While the usual daily dosages given above will meet the needs of most patients, there will be some who require doses greater than 4 mg/day. In such cases, dosage should be increased cautiously to avoid adverse effects.

In all patients, dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

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