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Metipranolol
METIPRANOLOL® FDA Package Insert
Indications and Usage
Dosage and Administration
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Overdosage
Description
Clinical Pharmacology
How Supplied/Storage and Handling
Patient Counseling Information
Labels and Packages
Clinical Trials on Metipranolol
ClinicalTrials.gov

Metipranolol

Clinical data
Trade names	Optipranolol
AHFS/Drugs.com	Micromedex Detailed Consumer Information
MedlinePlus	a601078
ATC code	S01ED04 (WHO) C07BA68 (WHO)
Identifiers
IUPAC name (RS)-4-{[-2-hydroxy-3-(isopropylamino)propyl]oxy}-2,3,6-trimethylphenyl acetate
CAS Number	22664-55-7
PubChem CID	31477
DrugBank	DB01214 Y
ChemSpider	29193 Y
UNII	X39AL81KEB
KEGG	D02374 Y
ChEMBL	ChEMBL1291 Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C17H27NO4
Molar mass	309.401 g/mol
3D model (JSmol)	Interactive image
SMILES O=C(Oc1c(c(c(OCC(O)CNC(C)C)cc1C)C)C)C
InChI InChI=1S/C17H27NO4/c1-10(2)18-8-15(20)9-21-16-7-11(3)17(22-14(6)19)13(5)12(16)4/h7,10,15,18,20H,8-9H2,1-6H3 Y Key:BQIPXWYNLPYNHW-UHFFFAOYSA-N Y
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms / Brand Names: METIPRANOLOL

Overview

Metipranolol hydrochloride (OptiPranolol) is a non-selective beta blocker used in eye drops to treat glaucoma.

Category

Beta Blockers

FDA Package Insert

METIPRANOLOL solution/ drops

Indications and Usage | Dosage and Administration | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Use in Specific Populations | Overdosage | Description | Clinical Pharmacology | How Supplied/Storage and Handling | Patient Counseling Information | Labels and Packages

Mechanism of Action

Metipranolol blocks beta1 and beta2 (non-selective) adrenergic receptors. It does not have significant intrinsic sympathomimetic activity, and has only weak local anesthetic (membrane-stabilizing) and myocardial depressant activity.