WBR0382

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Author [[PageAuthor::Rim Halaby, M.D. [1]]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Microbiology
Sub Category SubCategory::Genitourinary
Prompt [[Prompt::A 38 year old Caucasian male presents to the emergency department with fever and back pain that radiates to the inguinal area. Vital signs reveal a temperature of 38.5 degrees C (101 degrees F), heart rate of 98 beats per minute, and blood pressure measuring 122/88 mmHg. After appropriate work-up, the diagnosis of struvite stone is made. Stone culture and urine culture are performed; they reveal urea-splitting organism with swarming motility. What other characteristics does this organism have?]]
Answer A AnswerA::Oxidase-positive, catalase-positive, urease-positive
Answer A Explanation AnswerAExp::Proteus is not oxidase-positive.
Answer B AnswerB::Oxidase-negative, catalase-negative, urease-positive
Answer B Explanation AnswerBExp::Proteus is not catalase-positive
Answer C AnswerC::Oxidase-positive, catalase-negative, urease-negative
Answer C Explanation AnswerCExp::Proteus is none of the findings in option C.
Answer D AnswerD::Oxidase-negative, catalase-positive, urease-positive
Answer D Explanation AnswerDExp::Proteus mirabilis is correctly an oxidase-negative, catalase-positive, urease-positive organism
Answer E AnswerE::Oxidase-positive, catalase-positive, urease-negative
Answer E Explanation AnswerEExp::Proteus is not oxidase positive and not urease-negative.
Right Answer RightAnswer::D
Explanation [[Explanation::Proteus mirabilis is a common causative agent of struvite stones. It is an oxidase-negative, catalase-positive, urease-positive organism. It has a characteristic “swarming” motility in cultures. It is a known pathogen of the urogenital tract. Proteus is considered a urea-splitting organism, similar to Pseudomonas, Klebsiella, Staphylococcus, and Mycoplasma.

Educational Objective: Proteus mirabilis is a common causative agent of struvite stones. It is an oxidase-negative, catalase-positive, urease-positive organism with characteristic “swarming” motility.
Educational Objective:
References: ]]

Approved Approved::No
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