Ticlopidine description

Ticlopidine
Ticlopidine® FDA Package Insert
Indications and Usage
Dosage and Administration
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Overdosage
Description
Clinical Pharmacology
Nonclinical Toxicology
Clinical Studies
How Supplied/Storage and Handling
Patient Counseling Information
Labels and Packages
Clinical Trials on Ticlopidine
ClinicalTrials.gov

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]

Description

Ticlopidine hydrochloride is a platelet aggregation inhibitor. Chemically it is 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno [3,2-c] pyridine hydrochloride. The structural formula is:

Ticlopidine hydrochloride is a white crystalline solid. It is freely soluble in water and self-buffers to a pH of 3.6. It also dissolves freely in methanol, is sparingly soluble in methylene chloride and ethanol, slightly soluble in acetone and insoluble in a buffer solution of pH 6.3. It has a molecular weight of 300.25.

Ticlopidine HCl Tablets, USP for oral administration are provided as white to off-white, oval, unscored, film coated, imprinted tablets containing 250 mg of Ticlopidine Hydrochloride. Each tablet also contains croscarmellose sodium, microcrystalline cellulose and stearic acid as inactive ingredients. The white film coating contains hydroxypropyl methylcellulose, polyethylene glycol and titanium dioxide.

References

Adapted from the FDA Package Insert.