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- 14:12, 11 November 2015 Sujit Routray talk contribs uploaded File:Schematics of the process of metastasis 1.PNG ((a) Formation of metastatic tumor cell lines at primary sites like breast, lung, and skin (melanoma) seen as the red nodes. Metastasis from these primary sites then spreads to the brain via the circulatory system (red arrows) and also to adjacent sites...)