WBR0401
| Author | [[PageAuthor::Serge Korjian, M.D. (Reviewed by Serge Korjian)]] |
|---|---|
| Exam Type | ExamType::USMLE Step 1 |
| Main Category | MainCategory::Pharmacology |
| Sub Category | SubCategory::Cardiology, SubCategory::Vascular |
| Prompt | [[Prompt::The mechanism of action of a novel experimental drug is under investigation. The drug is intended to treat patients with atrial and ventricular arrhythmias who cannot tolerate other therapies. After initial rat testing, the core lab determines that the active molecule acts on the transmembrane proteins that regulate the resting membrane potential of cardiomyocytes. ECG monitoring demonstrates significant, dose-dependent increase in the QT interval in treated rats. Which of the following drugs is likely to be related to the experimental drug being evaluated?]] |
| Answer A | AnswerA::Sotalol |
| Answer A Explanation | AnswerAExp:: |
| Answer B | AnswerB::Procainamide |
| Answer B Explanation | AnswerBExp:: |
| Answer C | AnswerC::Propafenone |
| Answer C Explanation | AnswerCExp:: |
| Answer D | AnswerD::Metoprolol |
| Answer D Explanation | AnswerDExp:: |
| Answer E | AnswerE::Mexiletine |
| Answer E Explanation | AnswerEExp:: |
| Right Answer | RightAnswer::A |
| Explanation | [[Explanation:: Educational Objective: |
| Approved | Approved::Yes |
| Keyword | |
| Linked Question | Linked:: |
| Order in Linked Questions | LinkedOrder:: |