Acrokeratoelastoidosis of Costa

	Acrokeratoelastoidosis of Costa
	Classification and external resources
OMIM	101850
DiseasesDB	29804
eMedicine	article/1113926

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Overview

Acrokeratoelastoidosis of Costa (also known as "Keratoelastoidosis marginalis"^[1]) is a familial condition characterized by multiple keratotic papules on the dorsum of the hands and feet, palms, soles, in which electron microscopy shows rarified, abnormal elastic tissue.^[2]^:993^[3]^:214

It was characterized in 1953.^[4]

Diagnosis

Physical Examination

Skin

Feet

Acrokeratoelastoidosis. Adapted from Dermatology Atlas.^[5]
Acrokeratoelastoidosis. Adapted from Dermatology Atlas.^[5]
Acrokeratoelastoidosis. Adapted from Dermatology Atlas.^[5]
Acrokeratoelastoidosis. Adapted from Dermatology Atlas.^[5]
Acrokeratoelastoidosis. Adapted from Dermatology Atlas.^[5]

Treatments such as liquid nitrogen, salicylic acid, tretinoin, and prednisone have been tried, though with limited success.^[6]

References

↑ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
↑ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
↑ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
↑ Costa OG (1953). "Akrokerato-elastoidosis; a hitherto undescribed skin disease". Dermatologica. 107 (3): 164–8. doi:10.1159/000256794. PMID 13116681.
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 "Dermatology Atlas".
↑ Zhai Z, Yang X, Hao F (2006). "Acrokeratoelastoidosis". Eur J Dermatol. 16 (2): 201–2. PMID 16613753.

[Bolognia-1] Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.

[Fitz2-2] Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.

[Andrews-3] James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.

[pmid13116681-4] Costa OG (1953). "Akrokerato-elastoidosis; a hitherto undescribed skin disease". Dermatologica. 107 (3): 164–8. doi:10.1159/000256794. PMID 13116681.

[Dermatology_Atlas-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 "Dermatology Atlas".

[pmid16613753-6] Zhai Z, Yang X, Hao F (2006). "Acrokeratoelastoidosis". Eur J Dermatol. 16 (2): 201–2. PMID 16613753.

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