Hepatitis E primary prevention
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]
Overview
Prevention
Improving sanitation is the most important measure, which consists in proper treatment and disposal of human waste, higher standards for public water supplies, improved personal hygiene procedures and sanitary food preparation. Thus, prevention strategies of this disease are similar to those of many others that plague developing nations, and they require large-scale international financing of water supply and water treatment projects. A vaccine based on recombinant viral proteins has been developed and recently tested in a high-risk population (military personnel of a developing country).[1] The vaccine appeared to be effective and safe, but further studies are needed to assess the long-term protection and the cost-effectiveness of hepatitis E vaccination.
Guidelines for Epidemic Measures
The following measures should be observed in an epidemic situation:[2]
- Determination of the mode of transmission
- Identification of the population with an increased risk of infection
- Elimination of a common source of infection
- Improvement of sanitary and hygienic practices to eliminate faecal contamination of food and water
References
- ↑ Shrestha MP, Scott RM, Joshi DM; et al. (2007). "Safety and efficacy of a recombinant hepatitis E vaccine". N. Engl. J. Med. 356 (9): 895–903. doi:10.1056/NEJMoa061847. PMID 17329696.
- ↑ "Hepatitis E".