Tuberculosis differential diagnosis
|
Tuberculosis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Tuberculosis differential diagnosis On the Web |
|
American Roentgen Ray Society Images of Tuberculosis differential diagnosis |
|
Risk calculators and risk factors for Tuberculosis differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
Pulmonary tuberculosis must be differentiated from other diseases that cause cough, fever, night sweats, hemoptysis and weight loss, such as: brucellosis, bronchogenic carcinoma, Hodgkin lymphoma, bacterial pneumonia, sarcoidosis, mycoplasmal pneumonia.
Differential Diagnosis
Pulmonary Tuberculosis
| Disease | Findings |
|---|---|
| Bacterial pneumonia | Sudden onset of symptoms, such as high fever, cough, purulent sputum, chest pain. Consolidation on chest X-ray, leukocytosis. |
| Bronchogenic carcinoma | Can be asymptomatic, usually at older ages (> 50 years old), cough, hemoptysis, weight loss |
| Brucellosis | Fever, anorexia, night sweats, malaise,back pain , headache, and depression. History of exposure to infected animal |
| Hodgkin lymphoma | Fever, night sweats, pruritus, painless adenopathy, mediastinal mass |
| Mycoplasmal pneumonia | Gradual onset of dry cough, headache, malaise, sore throat. Diffuse bilateral infiltrates in chest X-ray. |
| Sarcoidosis | Non-caseating granulomas in lungs and other organs, bilateral hiliar adenopathy, predominantly in African American females. |
Extra-Pulmonary Tuberculosis
| Extra-Pulmonary Location | Differential Diagnosis |
|---|---|
| Tuberculous Lymphadenitis | Lymphoma, squamous cell carcinoma, papillary thyroid cancer, pyogenic infection |
| Skeletal Tuberculosis | Multiple myeloma, bone metastasis, spinal cord abscess, osteoporosis |
| Tuberculous Arthrits | Bacterial septic arthritis, pseudogout |
| Central Nervous System Tuberculosis | Bacterial meningitis, viral meningitis, encephalitis |
| Tuberculosis Peritonitis | Bacterial peritonitis, chronic peritoneal dialysis |
Adapted from Asian Spine J. Feb 2014; 8(1): 97–111[1]; Handbook of Clinical Neurology[2]; Circulation Dec 2005 vol.112 no.23 3608-3616[3]; Am J Trop Med Hyg 2013 vol. 88 no. 1 54-64[4] Clin Infect Dis.(2011)53(6):555-562.[5] |}
References
|
|