Enterovirus 68 historical perspective
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Human enterovirus 68 (EV-D68) was initially detected in 1962 from samples of 4 hospitalized children presenting for pneumonia and bronchiolitis in California. It is a rare disease that has recently become more evident. The most recent outbreak occurred in September 2014; it involved 10 states including Colorado, North Carolina, Georgia, Ohio, Iowa, Illinois, Missouri, Kansas, Oklahoma, and Kentucky.
Historical Perspective
Human enterovirus 68 (EV-D68) was initially detected in 1962 from samples of 4 hospitalized children presenting for pneumonia and bronchiolitis in California.[1] Prior to 2005, reports of EV-D68 infections were very limited. Only 26 cases of verified EV-D68 infection were documented between 1970 and 2005. It is considered one of the rarest infectious enteroviruses, representing approximately 0.1% of all enterovirus isolates in that time frame. Over the past few years, outbreaks of EV-D68 have been documented in Japan, the Philippines, and the Netherlands, as well as several clusters in the USA.[2] The most recent outbreak occurred in late August and September 2014, with clusters reported in 10 states including Colorado, North Carolina, Georgia, Ohio, Iowa, Illinois, Missouri, Kansas, Oklahoma, and Kentucky.
References
- ↑ Schieble, JH.; Fox, VL.; Lennette, EH. (1967). "A probable new human picornavirus associated with respiratory diseases". Am J Epidemiol. 85 (2): 297–310. PMID 4960233. Unknown parameter
|month=ignored (help) - ↑ Tokarz R, Firth C, Madhi SA, Howie SR, Wu W, Sall AA; et al. (2012). "Worldwide emergence of multiple clades of enterovirus 68". J Gen Virol. 93 (Pt 9): 1952–8. doi:10.1099/vir.0.043935-0. PMC 3542132. PMID 22694903.