Acrospiroma
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jesus Rosario Hernandez, M.D. [2].
Synonyms and keywords:: Nodular hidradenoma, poroma.
Overview
Acrospiroma (sometimes alternatively described as poroma) is a term used to refer to a benign adnexal tumor of the apical sweat gland (akral "peripheral" + spiroma "epithelial tumor of sweat gland").[1] Some authoritative sources use this term as a synonym for poroma,[2] and others use it as a broader designation that includes poroma and hidradenoma.[3] Under the general umbrella of sweat gland tumors derived from the apical portion of the secretory duct, there are several sub-types that are distinct by subtle histologic differences and slightly different clinical presentations. Specific types include:
- poromas
- hidroacanthoma simplex
- dermal duct tumor
- hidradenomas (nodular and clear cell sub-types)
Generally, these tumors can be of either eccrine or apocrine or even mixed-type sweat gland origin. Acrospiroma/poromas were traditionally thought to display purely eccrine differentiation, but it is now accepted that these tumors can be variable. Thus, it is more specific to classify any single tumor as a eccrine/apocrine sub-type of acrospiroma. This is in contrast to sub-types that have shown to be more purely eccrine differentiation, such as dermal duct tumors, hidroacanthoma simplex, or eccrine poromas.[4][5]
Acrospiromas are by definition benign, with malignant transformation very rare.[6] Surgical excision is usually curative and local recurrences are rare, although malignant tumors may metastasize.[4]
Physical Examination
Gallery
Head
- ↑ Laws RA, English JC 3rd, Elston DM (1996). "Acrospiroma: a case report and review". Cutis. 58 (5): 349–51. PMID 8934076.
- ↑ Bolognia, Jean (2008). Dermatology (in Deutsch). St. Louis, Mo: Mosby/Elsevier. ISBN 978-1-4160-2999-1.
- ↑ James, William (2011). Andrews' Diseases of the skin clinical dermatology. London: Saunders Elsevier. ISBN 978-1-4377-3619-9.
- ↑ 4.0 4.1 Griffiths, C; Cox, N; Breathnach, S; Burns, T, eds. (2010). "53. Tumours of the Skin Appendages: Eccrine or aprocrine/follicular tumours". Rook's Textbook of Dermatology - 8th Ed. Chichester, West Sussex: John Wiley & Sons Ltd. ISBN 1-4051-6169-8.
- ↑ Griffiths, C; Cox, N; Breathnach, S; Burns, T, eds. (2010). "53. Tumours of the Skin Appendages: Eccrine gland tumours". Rook's Textbook of Dermatology - 8th Ed. Chichester, West Sussex: John Wiley & Sons Ltd. ISBN 1-4051-6169-8.
- ↑ Hernandez, PE; Cestoni, PR (1985). "Nodular hidradenoma and hidradenocarcinoma. J Am Acad Dermatol 1985; 12: 15-20". J Am Acad Dermatol. 12: 15-20.