West nile virus causes
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Taxonomy
Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Flavivirus; Japanese encephalitis virus group[1]
Biology
West Nile virus has an icosahedral symmetry, with a smooth surface.[2] It is an enveloped virus with a nucleocapsid core built of RNA and capsid proteins. Its genome is contained in a single stranded mRNA virus of about 11000 bp.[3] It contains a single ORF, a 5' UTR, and a 3' region which is not translated.
Structure
Tropism
Natural Reservoir
Natural reservoirs of the West Nile virus include:[4]
- Humans
- 65 different species of mosquitos
- 326 species of birds
References
- ↑ "West Nile Virus".
- ↑ Mukhopadhyay, S. (2003). "Structure of West Nile Virus". Science. 302 (5643): 248–248. doi:10.1126/science.1089316. ISSN 0036-8075.
- ↑ Campbell, Grant L; Marfin, Anthony A; Lanciotti, Robert S; Gubler, Duane J (2002). "West Nile virus". The Lancet Infectious Diseases. 2 (9): 519–529. doi:10.1016/S1473-3099(02)00368-7. ISSN 1473-3099.
- ↑ Petersen LR, Brault AC, Nasci RS (2013). "West Nile virus: review of the literature". JAMA. 310 (3): 308–15. doi:10.1001/jama.2013.8042. PMID 23860989.