Multi-drug-resistant tuberculosis historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
Historical Perspective
Images from the History of Medicine (NLM) (http://ihm.nlm.nih.gov/images/B16691)
- Tuberculosis has been present in humans since antiquity. The earliest unambiguous detection of Mycobacterium tuberculosis was in the remains of bison, dated 18,000 BC.[1]
- However, whether tuberculosis originated in cattle and then transferred to humans, or diverged from a common ancestor, is currently unclear.[2]
- Through history tuberculosis had many names, such as phthisis and Wasting disease, which were mostly derived from its symptoms.
- The rod-shaped bacteria Mycobacterium tuberculosis was only identified in 1882 by Robert Koch.
- In the 19th and early 20th centuries, tuberculosis caused the most widespread public concern, being considered an endemic disease of the urban poor. In 1946, the development of streptomycin made possible the treatment and cure for tuberculosis.
- During the 1970s, multi-drug resistant mycobacterium tuberculosis was first described.
- In 1990, the DOTS strategy was first introduced by
References
- ↑ Rothschild B, Martin L, Lev G, Bercovier H, Bar-Gal G, Greenblatt C, Donoghue H, Spigelman M, Brittain D (2001). "Mycobacterium tuberculosis complex DNA from an extinct bison dated 17,000 years before the present". Clin Infect Dis. 33 (3): 305–11. PMID 11438894.
- ↑ Pearce-Duvet J (2006). "The origin of human pathogens: evaluating the role of agriculture and domestic animals in the evolution of human disease". Biol Rev Camb Philos Soc. 81 (3): 369–82. PMID 16672105.