Restless legs syndrome natural history, complications and prognosis

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Poor prognosis factors are:

• Genetics: Family members with RLS
• Symptoms during childhood and adolescence
• Sometimes serotoninergic antidepressants may worsen RLSDiagnostic and statistical manual of mental disorders : DSM-5. Washington, D.C: American Psychiatric Association. 2013. ISBN 0890425558.</ref>