Caspofungin
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]
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Overview
Caspofungin is {{{aOrAn}}} {{{drugClass}}} that is FDA approved for the {{{indicationType}}} of {{{indication}}}. Common adverse reactions include {{{adverseReactions}}}.
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
There is limited information regarding Caspofungin FDA-Labeled Indications and Dosage (Adult) in the drug label.
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Caspofungin in adult patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Caspofungin in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
There is limited information regarding Caspofungin FDA-Labeled Indications and Dosage (Pediatric) in the drug label.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Caspofungin in pediatric patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Caspofungin in pediatric patients.
Contraindications
There is limited information regarding Caspofungin Contraindications in the drug label.
Warnings
There is limited information regarding Caspofungin Warnings' in the drug label.
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Caspofungin Clinical Trials Experience in the drug label.
Postmarketing Experience
There is limited information regarding Caspofungin Postmarketing Experience in the drug label.
Drug Interactions
There is limited information regarding Caspofungin Drug Interactions in the drug label.
Use in Specific Populations
Pregnancy
Pregnancy Category (FDA):
There is no FDA guidance on usage of Caspofungin in women who are pregnant.
Pregnancy Category (AUS):
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Caspofungin in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Caspofungin during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Caspofungin in women who are nursing.
Pediatric Use
There is no FDA guidance on the use of Caspofungin in pediatric settings.
Geriatic Use
There is no FDA guidance on the use of Caspofungin in geriatric settings.
Gender
There is no FDA guidance on the use of Caspofungin with respect to specific gender populations.
Race
There is no FDA guidance on the use of Caspofungin with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Caspofungin in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Caspofungin in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Caspofungin in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Caspofungin in patients who are immunocompromised.
Administration and Monitoring
Administration
There is limited information regarding Caspofungin Administration in the drug label.
Monitoring
There is limited information regarding Caspofungin Monitoring in the drug label.
IV Compatibility
There is limited information regarding the compatibility of Caspofungin and IV administrations.
Overdosage
There is limited information regarding Caspofungin overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.
Pharmacology
There is limited information regarding Caspofungin Pharmacology in the drug label.
Mechanism of Action
There is limited information regarding Caspofungin Mechanism of Action in the drug label.
Structure
There is limited information regarding Caspofungin Structure in the drug label.
Pharmacodynamics
There is limited information regarding Caspofungin Pharmacodynamics in the drug label.
Pharmacokinetics
There is limited information regarding Caspofungin Pharmacokinetics in the drug label.
Nonclinical Toxicology
There is limited information regarding Caspofungin Nonclinical Toxicology in the drug label.
Clinical Studies
There is limited information regarding Caspofungin Clinical Studies in the drug label.
How Supplied
There is limited information regarding Caspofungin How Supplied in the drug label.
Storage
There is limited information regarding Caspofungin Storage in the drug label.
Images
Drug Images
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Package and Label Display Panel
{{#ask: Label Page::Caspofungin |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}
Patient Counseling Information
There is limited information regarding Caspofungin Patient Counseling Information in the drug label.
Precautions with Alcohol
Alcohol-Caspofungin interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
Brand Names
There is limited information regarding Caspofungin Brand Names in the drug label.
Look-Alike Drug Names
There is limited information regarding Caspofungin Look-Alike Drug Names in the drug label.
Drug Shortage Status
Price
References
The contents of this FDA label are provided by the National Library of Medicine.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [4]
Overview
Caspofungin (INN[1]) (brand name Cancidas worldwide) is a lipopeptide antifungal drug from Merck & Co., Inc.. It is a member of a new class of antifungals termed the echinocandins. It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin was the first inhibitor of fungal (1→3)-β-D-glucan synthesis to be approved by the United States Food and Drug Administration.[2] Caspofungin is administered intravenously.
Category
Antifungal
US Brand Names
CANCIDAS®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Clinical Studies | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
References
- ↑ European Medicines Agency's list of authorised medicines for human use (C)
- ↑ Deresinski SC; Stevens DA (2003). "Caspofungin". Clin Infect Dis. 36 (11): 1445&ndash, 1457. doi:10.1086/375080. PMID 12766841. Unknown parameter
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