Cardiac allograft vasculopathy medical therapy

Cardiac allograft vasculopathy Microchapters
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Overview
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Pathophysiology
Differentiating Cardiac allograft vasculopathy from other Diseases
Epidemiology and Demographics
Risk Factors
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Natural History, Complications and Prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]; Raviteja Guddeti, M.B.B.S. [3]

Overview

Once CAV has developed, pharmacologic options to halt progression are limited. Retransplantation is the only definitive treatment of established CAV. Ideal regimen should not affect the lipid profile, blood pressures and renal function, and have a positive impact on hemodynamics.

Medical Therapy

Treatment option for established CAV include:

Pharmacological Management	Non-pharmacological Interventions
Sirolimus Everolimus	Retransplantation Percutaneous coronary interventions Coronary artery bypass grafting (CABG) Transmyocardial revascularization Heparin induced/mediated extracorporeal LDL plasmapheresis (HELP)