Interferon-gamma
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alberto Plate [2]
Disclaimer
WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Please read our full disclaimer here.
Overview
Interferon-gamma is an immunological agent that is FDA approved for the treatment of serious infections associated with Chronic Granulomatous Disease and delaying time to disease progression in patients with severe, malignant osteopetrosis.. Common adverse reactions include {{{adverseReactions}}}.
Adult Indications and Dosage
FDA-Labeled Indications and Dosage (Adult)
There is limited information regarding Interferon-gamma FDA-Labeled Indications and Dosage (Adult) in the drug label.
Off-Label Use and Dosage (Adult)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Interferon-gamma in adult patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Interferon-gamma in adult patients.
Pediatric Indications and Dosage
FDA-Labeled Indications and Dosage (Pediatric)
There is limited information regarding Interferon-gamma FDA-Labeled Indications and Dosage (Pediatric) in the drug label.
Off-Label Use and Dosage (Pediatric)
Guideline-Supported Use
There is limited information regarding Off-Label Guideline-Supported Use of Interferon-gamma in pediatric patients.
Non–Guideline-Supported Use
There is limited information regarding Off-Label Non–Guideline-Supported Use of Interferon-gamma in pediatric patients.
Contraindications
There is limited information regarding Interferon-gamma Contraindications in the drug label.
Warnings
There is limited information regarding Interferon-gamma Warnings' in the drug label.
Adverse Reactions
Clinical Trials Experience
There is limited information regarding Interferon-gamma Clinical Trials Experience in the drug label.
Postmarketing Experience
There is limited information regarding Interferon-gamma Postmarketing Experience in the drug label.
Drug Interactions
There is limited information regarding Interferon-gamma Drug Interactions in the drug label.
Use in Specific Populations
Pregnancy
Pregnancy Category (FDA):
There is no FDA guidance on usage of Interferon-gamma in women who are pregnant.
Pregnancy Category (AUS):
There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Interferon-gamma in women who are pregnant.
Labor and Delivery
There is no FDA guidance on use of Interferon-gamma during labor and delivery.
Nursing Mothers
There is no FDA guidance on the use of Interferon-gamma in women who are nursing.
Pediatric Use
There is no FDA guidance on the use of Interferon-gamma in pediatric settings.
Geriatic Use
There is no FDA guidance on the use of Interferon-gamma in geriatric settings.
Gender
There is no FDA guidance on the use of Interferon-gamma with respect to specific gender populations.
Race
There is no FDA guidance on the use of Interferon-gamma with respect to specific racial populations.
Renal Impairment
There is no FDA guidance on the use of Interferon-gamma in patients with renal impairment.
Hepatic Impairment
There is no FDA guidance on the use of Interferon-gamma in patients with hepatic impairment.
Females of Reproductive Potential and Males
There is no FDA guidance on the use of Interferon-gamma in women of reproductive potentials and males.
Immunocompromised Patients
There is no FDA guidance one the use of Interferon-gamma in patients who are immunocompromised.
Administration and Monitoring
Administration
There is limited information regarding Interferon-gamma Administration in the drug label.
Monitoring
There is limited information regarding Interferon-gamma Monitoring in the drug label.
IV Compatibility
There is limited information regarding the compatibility of Interferon-gamma and IV administrations.
Overdosage
There is limited information regarding Interferon-gamma overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.
Pharmacology
Template:Px | |
Interferon-gamma
| |
Systematic (IUPAC) name | |
Human interferon gamma-1b | |
Identifiers | |
CAS number | 98059-61-1 |
ATC code | L03 |
PubChem | ? |
DrugBank | |
Chemical data | |
Formula | Template:OrganicBox atomTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBox atomTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBoxTemplate:OrganicBox |
Mol. mass | 17145.6 g/mol |
Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | ? |
Half life | ? |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
? |
Legal status | |
Routes | ? |
Mechanism of Action
There is limited information regarding Interferon-gamma Mechanism of Action in the drug label.
Structure
There is limited information regarding Interferon-gamma Structure in the drug label.
Pharmacodynamics
There is limited information regarding Interferon-gamma Pharmacodynamics in the drug label.
Pharmacokinetics
There is limited information regarding Interferon-gamma Pharmacokinetics in the drug label.
Nonclinical Toxicology
There is limited information regarding Interferon-gamma Nonclinical Toxicology in the drug label.
Clinical Studies
There is limited information regarding Interferon-gamma Clinical Studies in the drug label.
How Supplied
There is limited information regarding Interferon-gamma How Supplied in the drug label.
Storage
There is limited information regarding Interferon-gamma Storage in the drug label.
Images
Drug Images
{{#ask: Page Name::Interferon-gamma |?Pill Name |?Drug Name |?Pill Ingred |?Pill Imprint |?Pill Dosage |?Pill Color |?Pill Shape |?Pill Size (mm) |?Pill Scoring |?NDC |?Drug Author |format=template |template=DrugPageImages |mainlabel=- |sort=Pill Name }}
Package and Label Display Panel
{{#ask: Label Page::Interferon-gamma |?Label Name |format=template |template=DrugLabelImages |mainlabel=- |sort=Label Page }}
Patient Counseling Information
There is limited information regarding Interferon-gamma Patient Counseling Information in the drug label.
Precautions with Alcohol
Alcohol-Interferon-gamma interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.
Brand Names
There is limited information regarding Interferon-gamma Brand Names in the drug label.
Look-Alike Drug Names
There is limited information regarding Interferon-gamma Look-Alike Drug Names in the drug label.
Drug Shortage Status
Price
References
The contents of this FDA label are provided by the National Library of Medicine.
Interferon, gamma | |||
---|---|---|---|
Interferon gamma, line representation | |||
Identifiers | |||
Symbols | IFNG ; IFG; IFI | ||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 55526 | ||
RNA expression pattern | |||
More reference expression data | |||
Orthologs | |||
Template:GNF Ortholog box | |||
Species | Human | Mouse | |
Entrez | n/a | n/a | |
Ensembl | n/a | n/a | |
UniProt | n/a | n/a | |
RefSeq (mRNA) | n/a | n/a | |
RefSeq (protein) | n/a | n/a | |
Location (UCSC) | n/a | n/a | |
PubMed search | n/a | n/a |