Cefepime

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Cefepime
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alberto Plate [2]

Disclaimer

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Overview

Cefepime is a antibiotic (cephalosporin) that is FDA approved for the treatment of pneumonia, febrile neutropenia, uncomplicated UTI, uncomplicated skin infection and complicated intraabdominal infections. Common adverse reactions include rash, hypophosphatemia, diarrhea, Direct Coombs test positive, ALT/SGPT level raised, AST/SGOT level raised.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Cefepime in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Cefepime in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding Cefepime FDA-Labeled Indications and Dosage (Pediatric) in the drug label.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Cefepime in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Cefepime in pediatric patients.

Contraindications

There is limited information regarding Cefepime Contraindications in the drug label.

Warnings

There is limited information regarding Cefepime Warnings' in the drug label.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Cefepime Clinical Trials Experience in the drug label.

Postmarketing Experience

There is limited information regarding Cefepime Postmarketing Experience in the drug label.

Drug Interactions

There is limited information regarding Cefepime Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): There is no FDA guidance on usage of Cefepime in women who are pregnant.
Pregnancy Category (AUS): There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Cefepime in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Cefepime during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Cefepime in women who are nursing.

Pediatric Use

There is no FDA guidance on the use of Cefepime in pediatric settings.

Geriatic Use

There is no FDA guidance on the use of Cefepime in geriatric settings.

Gender

There is no FDA guidance on the use of Cefepime with respect to specific gender populations.

Race

There is no FDA guidance on the use of Cefepime with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Cefepime in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Cefepime in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Cefepime in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Cefepime in patients who are immunocompromised.

Administration and Monitoring

Administration

There is limited information regarding Cefepime Administration in the drug label.

Monitoring

There is limited information regarding Cefepime Monitoring in the drug label.

IV Compatibility

There is limited information regarding the compatibility of Cefepime and IV administrations.

Overdosage

There is limited information regarding Cefepime overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

There is limited information regarding Cefepime Pharmacology in the drug label.

Mechanism of Action

There is limited information regarding Cefepime Mechanism of Action in the drug label.

Structure

There is limited information regarding Cefepime Structure in the drug label.

Pharmacodynamics

There is limited information regarding Cefepime Pharmacodynamics in the drug label.

Pharmacokinetics

There is limited information regarding Cefepime Pharmacokinetics in the drug label.

Nonclinical Toxicology

There is limited information regarding Cefepime Nonclinical Toxicology in the drug label.

Clinical Studies

There is limited information regarding Cefepime Clinical Studies in the drug label.

How Supplied

There is limited information regarding Cefepime How Supplied in the drug label.

Storage

There is limited information regarding Cefepime Storage in the drug label.

Images

Drug Images

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Package and Label Display Panel

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Patient Counseling Information

There is limited information regarding Cefepime Patient Counseling Information in the drug label.

Precautions with Alcohol

Alcohol-Cefepime interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

There is limited information regarding Cefepime Brand Names in the drug label.

Look-Alike Drug Names

There is limited information regarding Cefepime Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.


Cefepime
MAXIPIME® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings
Precautions
Adverse Reactions
Overdosage
Clinical Studies
Dosage and Administration
Compatibility, Reconstitution, and Stability
Directions for Use
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]; Associate Editor(s)-in-Chief: Abdurahman Khalil, M.D. [4]

Overview

Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria, with greater activity against both Gram-negative and Gram-positive organisms than third-generation agents. Cefepime hydrochloride was first marketed in 1994 and is currently marketed under various trade names including Maxipime (Elan Pharma), Maxcef, Cepimax, Cepimex, and Axepim.

Category

Cephalosporin, Fourth-Generation

US Brand Names

MAXIPIME®

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings | Precautions | Adverse Reactions | Overdosage | Clinical Studies | Dosage and Administration | Compatibility, Reconstitution, and Stability | Directions For Use | How Supplied | Labels and Packages

Mechanism of Action

References