Interstitial nephritis causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Causes
Common causes include infection, or reaction to medication (such as an analgesic or antibiotics). 71%[1] to 92%[2] of cases are reported to be caused by drugs. This disease is also caused by other diseases and toxins that do damage to the kidney. Both acute and chronic tubulointerstitial nephritis can be caused by a bacterial infection in the kidneys, known as pyelonephritis. The most common cause is by an allergic reaction to a drug. The drugs that are known to cause this sort of reaction are antibiotics such as penicillin, and nonsteroidal anti-inflammatory drugs, such as aspirin. The time between exposure to the drug and the development of acute tubulointerstitial nephritis can be anywhere from 5 days to 5 weeks.
Causes in Alphabetical Order
- Acetaminophen (Tylenol)
- Acyclovir
- Aldomet
- Allopurinol
- Alpha-interferon
- Alport syndrome
- Amlodipine[3]
- Ampicillin
- Aristolochia
- Aspirin
- Azathioprine
- Bardet-Biedl syndrome
- Bumetanide
- Captopril
- Carbamazepine
- Cefotaxime sodium
- Cephalosporins
- Chlorthalidone
- Cimetidine
- Ciprofloxacin[4]
- Clofibrate
- Cocaine
- Creatine[5]
- Cytomegalovirus infection
- Diazepam
- Diclofenac
- Diflunisal
- Diltiazem[6]
- Diphenylhydantoin
- Diphtheria
- Doxycycline
- Epstein-Barr virus infection
- Erythromycin
- Ethambutol
- Famotidine
- Fenoprofen
- Furosemide
- Griseofulvin
- Hantaan virus
- HIV infection
- Hydralazine
- Hydrochlorothiazide
- Hypercalcimia
- Hyperkalaemic distal renal tubular acidosis
- Hyperuricemia
- Hypokalemia
- Ibuprofen
- Indinavir
- Indomethacin
- Isoniazid
- Kawasaki's disease
- Ketoprofen
- Lansoprazole
- Legionellosis
- Leishmaniasis
- Leptospirosis
- Macrolides
- Mesalamine
- Mesalazine[7]
- Methicillin
- Minocycline hydrochloride
- Mycoplasma infection
- Myeloma
- Naproxen
- Omeprazole[8]
- Omeprazole
- Oxacillin
- Oxytetracycline
- Penicillin
- Phenindione
- Phenobarbital
- Phenteramine[9]
- Phenylpropanolamine
- Phenytoin
- Piroxicam
- Polymyxin
- Pranlukast[10]
- Propylthioruacil[11]
- Quinine
- Ranitidine[12][13]
- Reflux nephropathy
- Renal failure
- Rickettsia infection
- Rifampin
- Rubeola infection
- Sensenbrenner syndrome
- Sicca syndrome
- Sickle cell disease
- Sjogren syndrome
- Streptococcal infection
- Streptomycin
- Sulfinpyrazone
- Sulindac
- Sulfonamide
- Syphilis
- Systemic lupus erythematosus
- Tenofovir disoproxil fumarate
- Tetracycline
- Thiazide diuretics
- Tolmetin
- Toxoplasmosis
- Triamterene
- Triamterene
- Trimethoprim-sulfamethoxazole
- Vancomycin[14]
- Wegener's granulomatosis
References
- ↑ Baker R, Pusey C (2004). "The changing profile of acute tubulointerstitial nephritis". Nephrol Dial Transplant. 19 (1): 8–11. PMID 14671029.
- ↑ Clarkson M, Giblin L, O'Connell F, O'Kelly P, Walshe J, Conlon P, O'Meara Y, Dormon A, Campbell E, Donohoe J (2004). "Acute interstitial nephritis: clinical features and response to corticosteroid therapy". Nephrol Dial Transplant. 19 (11): 2778–83. PMID 15340098.
- ↑ Ejaz AA, Fitzpatrick PM, Haley WE, Wasiluk A, Durkin AJ, Zachariah PK (2000). "Amlodipine besylate induced acute interstitial nephritis". Nephron. 85 (4): 354–6. PMID 10940749. Retrieved 2012-02-12. Unknown parameter
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ignored (help) - ↑ Andrews PA, Robinson GT (1999). "Intravascular haemolysis and interstitial nephritis in association with ciprofloxacin". Nephron. 83 (4): 359–60. PMID 10575299. Retrieved 2012-02-12.
- ↑ Koshy KM, Griswold E, Schneeberger EE (1999). "Interstitial nephritis in a patient taking creatine". The New England Journal of Medicine. 340 (10): 814–5. doi:10.1056/NEJM199903113401017. PMID 10075534. Retrieved 2012-02-12. Unknown parameter
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ignored (help) - ↑ Abadín JA, Durán JA, Pérez de León JA (1998). "Probable diltiazem-induced acute interstitial nephritis". The Annals of Pharmacotherapy. 32 (6): 656–8. PMID 9640485. Retrieved 2012-02-12. Unknown parameter
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ignored (help) - ↑ Corrigan G, Stevens PE (2000). "Review article: interstitial nephritis associated with the use of mesalazine in inflammatory bowel disease". Alimentary Pharmacology & Therapeutics. 14 (1): 1–6. PMID 10632639. Retrieved 2012-02-12. Unknown parameter
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ignored (help) - ↑ Post AT, Voorhorst G, Zanen AL (2000). "Reversible renal failure after treatment with omeprazole". The Netherlands Journal of Medicine. 57 (2): 58–61. PMID 10924942. Unknown parameter
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(help) - ↑ Markowitz GS, Tartini A, D'Agati VD (1998). "Acute interstitial nephritis following treatment with anorectic agents phentermine and phendimetrazine". Clinical Nephrology. 50 (4): 252–4. PMID 9799071. Unknown parameter
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(help) - ↑ Schurman SJ, Alderman JM, Massanari M, Lacson AG, Perlman SA (1998). "Tubulointerstitial nephritis induced by the leukotriene receptor antagonist pranlukast". Chest. 114 (4): 1220–3. PMID 9792602. Retrieved 2012-02-12. Unknown parameter
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ignored (help) - ↑ Fang JT, Huang CC (1998). "Propylthiouracil-induced acute interstitial nephritis with acute renal failure requiring haemodialysis: successful therapy with steroids". Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 13 (3): 757–8. PMID 9550661. Retrieved 2012-02-12. Unknown parameter
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ignored (help) - ↑ Gaughan WJ, Sheth VR, Francos GC, Michael HJ, Burke JF. Ranitidine-induced acute interstitial nephritis with epithelial cell foot process fusion. Am J Kidney Dis. 1993;22(2):337.
- ↑ Neelakantappa K, Gallo GR, Lowenstein J. Ranitidine-associated interstitial nephritis and Fanconi syndrome. Am J Kidney Dis. 1993;22(2):333.
- ↑ Wai AO, Lo AM, Abdo A, Marra F (1998). "Vancomycin-induced acute interstitial nephritis". The Annals of Pharmacotherapy. 32 (11): 1160–4. PMID 9825081. Retrieved 2012-02-12. Unknown parameter
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ignored (help)