Progressive multifocal leukoencephalopathy causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Causes
The cause of PML is a type of polyomavirus called the JC virus (JCV), after the initials of the patient in whom it was first discovered. The virus is widespread, with 86% of the general population presenting antibodies, but it usually remains latent, causing disease only when the immune system has been severely weakened.