Peripheral T-cell lymphomas

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

The REAL/WHO classification of T-cells NHL categorize them into Precursor T-cell neoplasm and Peripheral T-cell lymphomas/NK-cell neoplasms. The last one can be further subdivided into:

• T-cell CLL/prolymphocytic leukemia
• T-cell granular lymphocytic leukemia
• Mycosis fungoides/Sézary syndrome
• Peripheral T-cell lymphoma, not otherwise characterized
• Hepatosplenic gamma/delta T-cell lymphoma
• Subcutaneous panniculitis-like T-cell lymphoma
• Angioimmunoblastic T-cell lymphoma
• Extranodal T-/NK-cell lymphoma, nasal type
• Enteropathy-type intestinal T-cell lymphoma
• Adult T-cell lymphoma/leukemia (human T-lymphotrophic virus (HTLV-1))
• Anaplastic large cell lymphoma (primary systemic type)
• Anaplastic large cell lymphoma (primary cutaneous type)
• Aggressive NK-cell leukemia