Sandbox FN
Part 1
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Part 2
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References
See Also
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Treatment
Empiric therapy
Treatment options for high-risk patients
- Intravenous antibiotic monotherapy in hospital (for uncomplicated cases)
- Imipenem/cilastatin 500 mg IV every 6 h
- Meropenem 1 gram IV every 8 h
- Piperacillin/tazobactam 4.5 grams IV every 6 h
- Cefepime 2 grams IV every 8 h
- Ceftazidime 2 grams IV every 8 h
Treatment options for low-risk patients
- Intravenous antibiotics at home
- Daily long-acting intravenous agent ± oral therapy at home or office
- Oral antibiotic combination therapy†
- Ciprofloxacin + amoxicillin/clavulanate both at 500 mg every 8 h
- Moxifloxacin 400 mg every 24 h
- Ciprofloxacin 500 mg every 8 h + clindamycin 600 mg every 8 h (for penicillin-allergic patients)
- † Criteria for oral antibiotics: no nausea or vomiting, patient able to tolerate oral medications, and patient not on prior fluoroquinolone prophylaxis.
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