ESHAP regimen

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords:ESHAP Regimen; Etoposide-Solumedrol-High Dose Ara-C, Platinol Regimen

Overview

ESHAP regimen refers to a regimen consisting of etoposide, methylprednisolone (Solumedrol), high-dose cytarabine and cisplatin, used to treat relapsed and refractory Hodgkin's and Non-Hodgkin's lymphoma^[1]^[2] and rituximab added for the treatment of Diffuse large B-cell lymphoma. ^[3]

Regimen

EEtoposide

SMethylprednisolone (Solumedrol)

HHigh-dose

ACytarabine (Ara-c)

PCisplatin (Platinol)

Indications

Relapsed and refractory Hodgkin's and Non-Hodgkin's lymphoma^[1]^[4]

References

↑ ^1.0 ^1.1 Velasquez WS, McLaughlin P, Tucker S, Hagemeister FB, Swan F, Rodriguez MA; et al. (1994). "ESHAP--an effective chemotherapy regimen in refractory and relapsing lymphoma: a 4-year follow-up study". J Clin Oncol. 12 (6): 1169–76. PMID 8201379.
↑ "NCI Thesaurus".
↑ Montoro J, Andreola G, Gardellini A, Babic A, Negri M, Frungillo N; et al. (2014). "R-ESHAP plus pegfilgrastim as an effective peripheral stem cell mobilization regimen for autologous stem-cell transplantation in patients with relapsed/refractory diffuse large B-cell lymphoma". Transfus Apher Sci. 50 (3): 411–4. doi:10.1016/j.transci.2014.03.006. PMID 24751603.
↑ "NCI Thesaurus".

[pmid8201379-1] 1.0 ^1.1 Velasquez WS, McLaughlin P, Tucker S, Hagemeister FB, Swan F, Rodriguez MA; et al. (1994). "ESHAP--an effective chemotherapy regimen in refractory and relapsing lymphoma: a 4-year follow-up study". J Clin Oncol. 12 (6): 1169–76. PMID 8201379.

[2] "NCI Thesaurus".

[pmid24751603-3] Montoro J, Andreola G, Gardellini A, Babic A, Negri M, Frungillo N; et al. (2014). "R-ESHAP plus pegfilgrastim as an effective peripheral stem cell mobilization regimen for autologous stem-cell transplantation in patients with relapsed/refractory diffuse large B-cell lymphoma". Transfus Apher Sci. 50 (3): 411–4. doi:10.1016/j.transci.2014.03.006. PMID 24751603.

[4] "NCI Thesaurus".

[1]

[2]

[3]

[4]

ESHAP regimen

Overview

Regimen

Indications

References

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