Idrocilamide

Idrocilamide
Clinical data
Trade names	Talval, Srilane, Relaxnova, Brolitène
AHFS/Drugs.com	International Drug Names
Routes of; administration	Topical
ATC code	M02AX05 (WHO) ;
Identifiers
	IUPAC name N-(2-hydroxyethyl)-3-phenyl-2-propenamide;
CAS Number	6961-46-2 ;
PubChem CID	1550874;
ChemSpider	1267352 ;
UNII	6C816LUB1O;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C11H13NO2
Molar mass	191.226 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=C(\C=C\c1ccccc1)NCCO;
	InChI InChI=1S/C11H13NO2/c13-9-8-12-11(14)7-6-10-4-2-1-3-5-10/h1-7,13H,8-9H2,(H,12,14)/b7-6+ ; Key:OSCTXCOERRNGLW-VOTSOKGWSA-N ;
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Idrocilamide (trade names Talval, Srilane, Relaxnova, Brolitène^[1]^[2]) is a medication with skeletal muscle relaxant^[3] and anti-inflammatory actions^[4] used as a topical cream to treat lumbago and other kinds of muscular pain;^[5] it is available on prescription or over-the-counter^{[citation needed]} in France and various other countries.^[1]

Interactions

Idrocilamide has been reported to be a potent inhibitor of the metabolism of caffeine.^[6]^[7]

References

↑ ^1.0 ^1.1 Drugs.com: International Drug Names
↑ Drugfuture.com: Idrocilamide
↑ PMID 2085796 (PMID 2085796)
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↑ Bannwarth B, Le Huec JC, Vinçon G; et al. (December 1993). "[Tissue and systemic diffusion of idrocilamide after cutaneous administration]". Rev Rhum Ed Fr (in French). 60 (12): 932–6. PMID 8012322.
↑ PMID 2140002 (PMID 2140002)
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↑ Carrillo JA, Benitez J (August 2000). "Clinically significant pharmacokinetic interactions between dietary caffeine and medications". Clin Pharmacokinet. 39 (2): 127–53. doi:10.2165/00003088-200039020-00004. PMID 10976659.
↑ Brazier JL, Descotes J, Lery N, Ollagnier M, Evreux JC (January 1980). "Inhibition by idrocilamide of the disposition of caffeine". Eur. J. Clin. Pharmacol. 17 (1): 37–43. doi:10.1007/bf00561675. PMID 7371698.

Template:Topical products for joint and muscular pain

Template:Musculoskeletal-drug-stub

[Drugs.com-1] 1.0 ^1.1 Drugs.com: International Drug Names

[2] Drugfuture.com: Idrocilamide

[3] PMID 2085796 (PMID 2085796)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand

[pmid8012322-4] Bannwarth B, Le Huec JC, Vinçon G; et al. (December 1993). "[Tissue and systemic diffusion of idrocilamide after cutaneous administration]". Rev Rhum Ed Fr (in French). 60 (12): 932–6. PMID 8012322.

[5] PMID 2140002 (PMID 2140002)
Citation will be completed automatically in a few minutes. Jump the queue or expand by hand

[pmid10976659-6] Carrillo JA, Benitez J (August 2000). "Clinically significant pharmacokinetic interactions between dietary caffeine and medications". Clin Pharmacokinet. 39 (2): 127–53. doi:10.2165/00003088-200039020-00004. PMID 10976659.

[pmid7371698-7] Brazier JL, Descotes J, Lery N, Ollagnier M, Evreux JC (January 1980). "Inhibition by idrocilamide of the disposition of caffeine". Eur. J. Clin. Pharmacol. 17 (1): 37–43. doi:10.1007/bf00561675. PMID 7371698.

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Idrocilamide

Interactions

References

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