Atipamezole

Atipamezole
Clinical data
AHFS/Drugs.com	International Drug Names
ATCvet code	Template:Infobox drug/formatATCvet; Template:Infobox drug/formatATCvet;
Legal status
Legal status	Veterinary use only;
Identifiers
	IUPAC name 4-(2-Ethyl-1,3-dihydroinden-2-yl)-3H-imidazole;
CAS Number	104054-27-5 ;
PubChem CID	71310;
ChemSpider	64427 ;
UNII	03N9U5JAF6;
KEGG	D03002 ;
ChEMBL	ChEMBL353972 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C14H16N2
Molar mass	212.290 g/mol
3D model (JSmol)	Interactive image;
	SMILES n1cc(nc1)C3(Cc2c(cccc2)C3)CC;
	InChI InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16) ; Key:HSWPZIDYAHLZDD-UHFFFAOYSA-N ;
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Atipamezole (brand name Antisedan, Pfizer) is a synthetic α₂ adrenergic receptor antagonist, indicated for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs.^[1] It has also been researched in humans as a potential anti-Parkinsonian drug.^[2]

References

↑ Pfizer Animal Health ANTISEDAN Product Overview
↑ Pertovaara A, Haapalinna A, Sirviö J, Virtanen R (2005). "Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist". CNS Drug Reviews. 11 (3): 273–88. doi:10.1111/j.1527-3458.2005.tb00047.x. PMID 16389294.