Alimemazine

Alimemazine

Clinical data
Pregnancy category	AU: C
Routes of administration	Oral
ATC code	D04AA10 (WHO) R06AD02 (WHO), R06AD05 (WHO)
Pharmacokinetic data
Metabolism	Hepatic
Identifiers
IUPAC name N,N,2-trimethyl-3-phenothiazin-10-yl-propan-1-amine
CAS Number	84-96-8
PubChem CID	5574
DrugBank	APRD00258
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C18H22N2S
Molar mass	298.447 g/mol

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Alimemazine (INN), also known as trimeprazine (former BAN and USAN; trade names Nedeltran, Panectyl, Repeltin, Therafene, Theralen, Theralene, Vallergan, Vanectyl, or Temaril), commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine). It also acts as a sedative and anti-emetic for prevention of motion sickness. Although it is structurally related to drugs such as chlorpromazine (Thorazine), it is not used as an anti-psychotic treatment. It is no longer available in the United States.