Perflubron

Perflubron

Clinical data
ATC code	V08CX01 (WHO)
Identifiers
IUPAC name 1-Bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane
CAS Number	423-55-2
PubChem CID	9873
ChemSpider	9489
ChEMBL	ChEMBL1200866
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C8BrF17
Molar mass	498.96 g/mol
3D model (JSmol)	Interactive image
Density	1.93 g/cm3
Melting point	6 °C (42.8 °F)
Boiling point	142 °C (287.6 °F)
SMILES FC(F)(C(F)(F)C(Br)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
InChI InChI=1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26 Key:WTWWXOGTJWMJHI-UHFFFAOYSA-N

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Perflubron (INN/USAN, or perfluorooctyl bromide; brand name Imagent) is a contrast medium for magnetic resonance imaging, computer tomography and sonography. It was approved for this use in the United States by the Food and Drug Administration in 1993.

Experimental research

Perflubron has also been tested experimentally for use in liquid breathing in premature infants with respiratory distress.

See also Liquid breathing#Medical treatment for more information on this potential application.

This molecular model of Perflubron is color-coded by electron density to illustrate the positive polarisation of the large bromine atom by the inductively electron-withdrawing perfluorooctyl chain.