Bromisoval

Bromisoval
	Skeletal formula of bromisoval
Names
	IUPAC name (RS)-2-Bromo-N-carbamoyl-3-methylbutanamide[citation needed]
Identifiers
CAS Number	496-67-3 ; 27109-49-5 R ;
3D model (JSmol)	Interactive image; Interactive image;
ChEBI	CHEBI:31304;
ChEMBL	ChEMBL1515611 ;
ChemSpider	2353 ; 129594 R ; 643139 S ;
ECHA InfoCard	Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value). Lua error in Module:Wikidata at line 879: attempt to index field 'wikibase' (a nil value).
KEGG	D01391;
MeSH	Bromisovalum
PubChem CID	2447; 146955 R; 735997 S;
UNII	469GW8R486 ;
	InChI InChI=1S/C6H11BrN2O2/c1-3(2)4(7)5(10)9-6(8)11/h3-4H,1-2H3,(H3,8,9,10,11) Key: CMCCHHWTTBEZNM-UHFFFAOYSA-N ;
	SMILES CC(C)C(Br)c(:[o]):[nH]:c(:[nH2]):[o]; CC(C)C(Br)C(=O)NC(N)=O;
Properties
Chemical formula	C6H11BrN2O2
Molar mass	223.07 g·mol−1
Related compounds
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Bromisoval (INN; commonly known as bromvalerylurea) is a hypnotic and sedative discovered by Knoll in 1907 and patented in 1909.^[1] It is marketed over the counter in Asia under various trade names (such as Brovarin^[2]), usually in combination with non-steroidal anti-inflammatory drugs.

Chronic use of bromisoval has been associated with bromine poisoning.^[3]^[4]^[5]^[6]

References

↑ US patent 914518, Saam, E., "Alpha-halogen-isovaleryl-urea and process of making the same", issued 1909-03-09, assigned to Knoll
↑ "Bromisoval". International. Drugs.com.
↑ PMID 11605223 (PMID 11605223)
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↑ PMID 9804091 (PMID 9804091)
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↑ PMID 15972320 (PMID 15972320)
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↑ PMID 9372340 (PMID 9372340)
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