Climazolam

Climazolam
Clinical data
AHFS/Drugs.com	International Drug Names
ATCvet code	Template:Infobox drug/formatATCvet; Template:Infobox drug/formatATCvet;
Identifiers
	IUPAC name 8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine;
CAS Number	59467-77-5;
PubChem CID	68790;
ChemSpider	62030;
UNII	O9KZB9HG1Y;
KEGG	D07714;
ChEMBL	ChEMBL2104070;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C18H13Cl2N3
Molar mass	342.222
3D model (JSmol)	Interactive image;
	SMILES ClC1=CC=CC=C1C2=NCC3=CN=C(C)N3C4=C2C=C(C=C4)Cl;

Climazolam^[1] (Ro21-3982) was introduced under licence as a veterinary medicine by the Swiss Pharmacutical company Gräub under the tradename 'Climasol'.^[2] Climazolam is a benzodiazepine, specifically an imidazo benzodiazepine derivative developed by Hoffman-LaRoche. It is similar in structure to triazolam and is used in veterinary medicine for anesthetizing animals.^[3]^[4]

References

↑ US 4280957 - Imidazodiazepines and processes therefor
↑ http://www.drugs.com/international/climazolam.html
↑ Ganter M, Kanngiesser M (Aug 1991). "Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine". Zentralbl Veterinarmed A (in German). 38 (7): 501–509. PMID 195024.
↑ Bettschart-Wolfensberger R, Taylor PM, Sear JW, Bloomfield MR, Rentsch K, Dawling S (Oct 1996). "Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam-ketamine combination in ponies premedicated with acepromazine and xylazine". American Journal of Veterinary Research. 57 (10): 1472–1427. PMID 8896687.

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[1] US 4280957 - Imidazodiazepines and processes therefor

[2] ttp://www.drugs.com/international/climazolam.html

[3] Ganter M, Kanngiesser M (Aug 1991). "Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine". Zentralbl Veterinarmed A (in German). 38 (7): 501–509. PMID 195024.

[4] Bettschart-Wolfensberger R, Taylor PM, Sear JW, Bloomfield MR, Rentsch K, Dawling S (Oct 1996). "Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam-ketamine combination in ponies premedicated with acepromazine and xylazine". American Journal of Veterinary Research. 57 (10): 1472–1427. PMID 8896687.

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[2]

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[4]

Climazolam

References

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