Lassa fever history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Ammu Susheela, M.D. [2]
Synonyms and keywords: Lassa hemorrhagic fever; LHF
Overview
Lassa fever after an incubation period of six to twenty-one days, an acute illness with multiorgan involvement develops gastrointestinal, neurological and pulmonary symptoms.
History
In 80% of cases the disease is inapparent, but in the remaining 20% it takes a complicated course. After an incubation period of six to twenty-one days, an acute illness with multiorgan involvement develops.[1]
Common Symptoms
Non-specific symptoms include fever, facial swelling, muscle fatigue, conjunctivitis, retrosternal pain (pain behind the chest wall), sore throat, back pain, cough, abdominal pain, vomiting, diarrhea, proteinuria (protein in the urine) and mucosal bleeding.
Because the symptoms of Lassa fever are so varied and nonspecific, clinical diagnosis is often difficult.
Less Common Symptoms
The other symptoms arising from the affected organs are:
- Gastrointestinal tract
- Cardiovascular system
- Chest pain
- High blood pressure
- Low blood pressure
- [Abnormally high heart rate
- Respiratory tract
- Nervous system
- Headache
- Tremor
- Unilateral or bilateral hearing loss
- Seizures