Basal cell carcinoma medical therapy
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Overview
Basal Cell Carcinoma Medical Therapy
After the suspicious lesion is evaluated, the medical therapy is divided into low-risk and high-risk basal carcinoma patients.
The table below summarizes the characteristics in low-risk and high-risk lesions[1].
| H&P | Low Risk | High Risk |
| Location/size | Area L <20 mm; Area M <10 mm; Area H <6 mm | Area L ≥20 mm; Area M ≥10 mm; Area H ≥6 mm |
| Borders | Well defined | Poorly defined |
| Primary vs. recurrent | Primary | Recurrent |
| Immunosuppression | (-) | (+) |
| Site of prior radiation therapy | (-) | (+) |
| Subtype | Nodular, superficial | Aggressive growth pattern |
| Perineural involvement | (-) | (+) |
Area H = “mask areas” of face (central face, eyelids, eyebrows, periorbital, nose, lips [cutaneous and vermilion], chin, mandible, preauricular and postauricular skin/sulci, temple, ear), genitalia, hands, and feet
Area M = cheeks, forehead, scalp, neck, and pre tibia
Area L = trunk and extremities (excluding pretibia, hands, feet, nail units, and ankles)
The algorithm below demonstrates a treatment protocol for low-risk lesions[2].
The algorithm below demonstrates a treatment protocol for high-risk lesions[3].