Paraoxon

Paraoxon

Clinical data
ATC code	S01EB10 (WHO)
Legal status
Legal status	In general: uncontrolled
Identifiers
IUPAC name diethyl 4-nitrophenyl phosphate
CAS Number	311-45-5 Y
PubChem CID	9395
ChemSpider	9026 Y
UNII	Q9CX8P80JW
ChEBI	CHEBI:27827 N
ChEMBL	ChEMBL23838 Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C10H14NO6P
Molar mass	275.195 g/mol
3D model (JSmol)	Interactive image
SMILES [O-][N+](=O)c1ccc(OP(=O)(OCC)OCC)cc1
InChI InChI=1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3 Y Key:WYMSBXTXOHUIGT-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

WikiDoc Resources for Paraoxon
Articles
Most recent articles on Paraoxon Most cited articles on Paraoxon Review articles on Paraoxon Articles on Paraoxon in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Paraoxon Images of Paraoxon Photos of Paraoxon Podcasts & MP3s on Paraoxon Videos on Paraoxon
Evidence Based Medicine
Cochrane Collaboration on Paraoxon Bandolier on Paraoxon TRIP on Paraoxon
Clinical Trials
Ongoing Trials on Paraoxon at Clinical Trials.gov Trial results on Paraoxon Clinical Trials on Paraoxon at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Paraoxon NICE Guidance on Paraoxon NHS PRODIGY Guidance FDA on Paraoxon CDC on Paraoxon
Books
Books on Paraoxon
News
Paraoxon in the news Be alerted to news on Paraoxon News trends on Paraoxon
Commentary
Blogs on Paraoxon
Definitions
Definitions of Paraoxon
Patient Resources / Community
Patient resources on Paraoxon Discussion groups on Paraoxon Patient Handouts on Paraoxon Directions to Hospitals Treating Paraoxon Risk calculators and risk factors for Paraoxon
Healthcare Provider Resources
Symptoms of Paraoxon Causes & Risk Factors for Paraoxon Diagnostic studies for Paraoxon Treatment of Paraoxon
Continuing Medical Education (CME)
CME Programs on Paraoxon
International
Paraoxon en Espanol Paraoxon en Francais
Business
Paraoxon in the Marketplace Patents on Paraoxon
Experimental / Informatics
List of terms related to Paraoxon

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Paraoxon is a parasympathomimetic which acts as an acetylcholinesterase inhibitor. It is an organophosphate oxon, and the active metabolite of the insecticide parathion. It is also used as an ophthalmological drug against glaucoma. Paraoxon is one of the most potent acetylcholinesterase-inhibiting insecticides available, around 70% as potent as the nerve agent sarin, and so is now rarely used as an insecticide due to the risk of poisoning to humans and other animals. It is easily absorbed through skin, and was used as an assassination weapon by the apartheid-era South African chemical weapons program Project Coast.