Tocofersolan

Template:Chembox E number

Tocofersolan

Names
IUPAC name α-[4-[[(2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl]oxy]-1,4-dioxobutyl]-ω-hydroxy-poly(oxy-1,2-ethanediyl)
Other names Tocofersolan; Vitamin E PEG succinate; α-Tocopherol polyethylene glycol succinate; Liqui-E
Identifiers
CAS Number	9002-96-4
3D model (JSmol)	Interactive image
ChemSpider	64498 Y
ECHA InfoCard
PubChem CID	9938056
UNII	O03S90U1F2 Y
InChI InChI=1S/C35H58O6/c1-24(2)12-9-13-25(3)14-10-15-26(4)16-11-20-35(8)21-19-30-29(7)33(27(5)28(6)34(30)41-35)40-32(38)18-17-31(37)39-23-22-36/h24-26,36H,9-23H2,1-8H3 Y Key: AOBORMOPSGHCAX-UHFFFAOYSA-N Y InChI=1/C35H58O6/c1-24(2)12-9-13-25(3)14-10-15-26(4)16-11-20-35(8)21-19-30-29(7)33(27(5)28(6)34(30)41-35)40-32(38)18-17-31(37)39-23-22-36/h24-26,36H,9-23H2,1-8H3 Key: AOBORMOPSGHCAX-UHFFFAOYAU
SMILES O=C(OCCO)CCC(=O)Oc2c(c(c1OC(CCc1c2C)(C)CCCC(C)CCCC(C)CCCC(C)C)C)C
Properties
Chemical formula	(C2H4O)nC33H54O5
Molar mass	Variable
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

WikiDoc Resources for Tocofersolan
Articles
Most recent articles on Tocofersolan Most cited articles on Tocofersolan Review articles on Tocofersolan Articles on Tocofersolan in N Eng J Med, Lancet, BMJ
Media
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Evidence Based Medicine
Cochrane Collaboration on Tocofersolan Bandolier on Tocofersolan TRIP on Tocofersolan
Clinical Trials
Ongoing Trials on Tocofersolan at Clinical Trials.gov Trial results on Tocofersolan Clinical Trials on Tocofersolan at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Tocofersolan NICE Guidance on Tocofersolan NHS PRODIGY Guidance FDA on Tocofersolan CDC on Tocofersolan
Books
Books on Tocofersolan
News
Tocofersolan in the news Be alerted to news on Tocofersolan News trends on Tocofersolan
Commentary
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Definitions
Definitions of Tocofersolan
Patient Resources / Community
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Healthcare Provider Resources
Symptoms of Tocofersolan Causes & Risk Factors for Tocofersolan Diagnostic studies for Tocofersolan Treatment of Tocofersolan
Continuing Medical Education (CME)
CME Programs on Tocofersolan
International
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Business
Tocofersolan in the Marketplace Patents on Tocofersolan
Experimental / Informatics
List of terms related to Tocofersolan

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Tocofersolan (INN) or tocophersolan is a synthetic water-soluble version of vitamin E. Natural forms of vitamin E are fat soluble, but not water-soluble. Tocofersolan is polyethylene glycol derivative of α-tocopherol that enables water solubility.

Tocofersolan is used as a vitamin E supplement or to treat vitamin E deficiency in individuals who cannot absorb fats due to disease. On 24 July 2009 the European Medicines Agency approved tocofersolan under the trade name Vedrop 50 mg/ml oral solution for the treatment of vitamin E deficiency due to digestive malabsorption in paediatric patients suffering from congenital or hereditary chronic cholestasis, from birth (in term newborns) to 16 or 18 years of age (depending on the region).

Tocofersolan is also used in cosmetics and pharmaceuticals as an antioxidant.