Myxoma history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [3]
Overview
Atrial myxoma Symptoms may occur at any time, but most often they tend happen with change in body position, left atrial myxoma symptoms may mimic mitral stenosis, right atrial myxomas rarely produce symptoms until they have grown to be at least 13 cm (about 5 inches) wide, general symptoms may also mimic those of infective endocarditis.
History
Symptoms associated with cardiac myxomas are typically due to the effect of the mass of the tumor obstructing the normal blood flow within the heart champers.
Some symptoms of myxoma may be associated with the release of interleukin 6 (IL-6) by the myxoma.[1][2]
Common Symptoms
- platypnea, (breathing difficulty that is relieved when lying flat)
- Orthopenea
- Chest pain or tightness
- Dizziness
- Fainting
- palpitations
- Shortness of breath with activity
- Lightheadedness or syncope
- Hemoptysis
- Sudden death
- Blueness of skin, especially the fingers (Raynaud's phenomenon)
- Cough
- clubbing of the fingers
- Fever
- Fingers that change color upon pressure or with cold or stress
- malaise
- Unexplained weight loss
- Joint pain
- Edema
References
- ↑ Seino Y, Ikeda U, Shimada K. (1993). "Increased expression of interleukin 6 mRNA in cardiac myxomas". Br Heart J. 69 (6): 565–7. PMID 8343326.
- ↑ Jourdan M, Bataille R, Seguin J, Zhang XG, Chaptal PA, Klein B (1990). "Constitutive production of interleukin-6 and immunologic features in cardiac myxomas". Arthritis Rheum. 33 (3): 398–402. PMID 1690543.