Craniopharyngioma differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Differentiating Craniopharyngioma from other Diseases
Craniopharyngioma is a mass in the pituitary region. A simple and popular mnemonic to remember the common pituitary masses that can be confused with craniopharyngioma is SATCHMO.[1]
- S: Sarcoid, sellar tumour (pituitary adenoma)
- A: Aneurysm
- T: Teratoma or tuberculosis (and other granulomatous diseases)
- C: Cleft cyst (Rathke), chordoma
- H: Hypothalamic glioma, hamartoma of tuber cinereum, histiocytosis
- M: Meningioma, metastasis
- O: Optic nerve glioma
General imaging differential considerations include:
- Rathke cleft cyst
- No solid or enhancing component
- Calcification is rare
- Unilocular
- Majority are completely or mostly intrasellar
- Pituitary macroadenoma (with cystic degeneration or necrosis)
- Can look very similar
- Usually has intrasellar epicentre with pituitary fossa enlargement rather than suprasellar epicentre
- Despite occasional presence of T1 bright cystic regions, calcification in these cases is often absent (whereas most adamantinomatous craniopharyngiomas are calcified)
- Intracranial teratoma
- Presence of fat is helpful, but requires fat saturated sequences or CT to confirm
References
- ↑ Differtials of Craniopharyngioma. Dr Henry Knipe and Dr Daryl Bergen et al. Radiopaedia. http://radiopaedia.org/articles/pituitary-region-masses-mnemonic-1