Langerhans cell histiocytosis epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Epidemiology
LCH histiocytosis usually affects children of between 1 and 15 years old and peak incidence is between age 5 and 10. Among children under the age of 10, yearly incidence is thought to be 1 in 200,000[1]; and in adults even more rare, in about 1 in 560,000.[2] It has been reported in elderly but is vanishingly rare[3]. commoner in white race and boys are effected twice as often as girls.
LCH is usually sporadic and non-hereditary condition but familial clustering has been noted in limited number of cases. Hashimoto-Pritzker disease, a variant of Hand-Schüller-Christian disease, is a congenital self-healing form[4].
References
- ↑ "MedlinePlus Medical Encyclopedia: Histiocytosis". Retrieved 2007-05-10.
- ↑ "Histiocytosis Association of Canada". Retrieved 2007-05-16.
- ↑ Gerlach B, Stein A, Fischer R, Wozel G, Dittert D, Richter G (1998). "[Langerhans cell histiocytosis in the elderly]". Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete (in German). 49 (1): 23–30. PMID 9522189.
- ↑ Kapur P, Erickson C, Rakheja D, Carder K, Hoang M (2007). "Congenital self-healing reticulohistiocytosis (Hashimoto-Pritzker disease): ten-year experience at Dallas Children's Medical Center". J. Am. Acad. Dermatol. 56 (2): 290–4. PMID 17224372.