Diffuse large B cell lymphoma laboratory tests
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory tests helpful in the diagnosis of diffuse large B cell lymphoma include complete blood count, LDH, and lymph node biopsy
Laboratory Tests
Laboratory studies include[1]
- Complete blood count
- Serum lactate dehydrogenase (LDH)
- Comprehensive metabolic panel
- Lymph node or extranodal tissue biopsy
- CT chest/abdominal/pelvic with oral and intravenous contrast (unless co-existent renal insufficiency)
- MUGA scan or echocardiograms are recommended when anthracyclines and anthracenedione containing regimens are used
- Bone marrow biopsy with or without aspirate is essential in all cases where treatment is considered; however, there are circumstances where it may be deferred
- Hepatitis B testing prior to initiation of treatment in all patients who will receive anti CD20 monoclonal antibody-based regimens and anyone with a risk factor
- Hepatitis C testing is needed in high-risk patients