Uterine cancer natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Natural History

Complications

Complications may include anemia due to blood loss. A perforation (hole) of the uterus may occur during a D and C or endometrial biopsy.

There can also be complications from hysterectomy, radiation, and chemotherapy.

Prognosis

5-Year Survival

  • Between 2004 and 2010, the 5-year relative survival of patients with uterine cancer was 83.2%.[1]
  • When stratified by age, the 5-year relative survival of patients with uterine cancer was 86.6% and 73.1% for patients <65 and ≥ 65 years of age respectively.[1]
  • The survival of patients with uterine cancer varies with the stage of the disease. Shown below is a table depicting the 5-year relative survival by the stage of uterine cancer:[1]
Stage 5-year relative survival (%), (2004-2010)
All stages 81.5%
Localized 95.1%
Regional 67.7%
Distant 17,5%
Unstaged 47.9%
  • Shown below is an image depicting the 5-year conditional relative survival (probability of surviving in the next 5-years given the cohort has already survived 0, 1, 3 years) between 1998 and 2010 of uterine cancer by stage at diagnosis according to SEER. These graphs are adapted from SEER: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.[1]

5-year conditional relative survival (probability of surviving in the next 5-years given the cohort has already survived 0, 1, 3 years) between 1998 and 2010 of uterine cancer by stage at diagnosis according to SEER

References

  1. 1.0 1.1 1.2 1.3 Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.


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