Retinoblastoma classification
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Classification
- The International Retinoblastoma Staging System (IRSS) may be used for staging retinoblastoma.
- Stage 0
- Stage I
- Stage II
- Stage III
- Stage IV
- The IRSS stages are based on how much cancer remains after surgery to remove the tumor and whether the cancer has spread.
- Stage 0
- The tumor is in the eye only. The eye has not been removed and the tumor was treated without surgery.
- Stage I
- The tumor is in the eye only. The eye has been removed and no cancer cells remain.
- Stage II
- The tumor is in the eye only. The eye has been removed and there are cancer cells left that can be seen only with a microscope.
- Stage III
- Stage III is divided into
- stages IIIa and
- stages IIIb
- In stage IIIa, cancer has spread from the eye to tissues around the eye socket.
- In stage IIIb, cancer has spread from the eye to lymph nodes near the ear or in the neck.
- Stage IV
- Stage IV is divided into
- stages IVa and
- stages IVb
- In stage IVa, cancer has spread to the blood but not to the brain or spinal cord. One or more tumors may have spread to other parts of the body such as the bone or liver.
- In stage IVb, cancer has spread to the brain or spinal cord. It also may have spread to other parts of the body.